Kidneys

eGFR (Combined)

eGFR (average) combines both creatinine and Cystatin C-based estimates, offering a more accurate picture of kidney health across diverse individuals.

What it is

eGFR (average) combines both creatinine and Cystatin C-based estimates, offering a more accurate picture of kidney health across diverse individuals. This dual-marker method balances out the limitations of each test, helping identify early dysfunction with greater confidence. It's ideal for catching early signs of kidney disease and preventing long-term damage.

What affects your levels

A low eGFR (average) may reflect true impairment in kidney filtration due to chronic disease, poor circulation, inflammation, or metabolic overload. It removes muscle mass and dietary biases seen in isolated methods. Early drops can signal systemic stress on the kidneys, even in those with normal lab values otherwise.

Signs and symptoms

Early stages may be silent. As eGFR drops, you may experience fatigue, puffiness, changes in urination, or blood pressure elevation. Regular testing of average eGFR enables earlier detection and helps tailor lifestyle changes to stabilize kidney function and metabolic health.

Foods that help

Choose kidney-protective foods like cauliflower, garlic, apples, and olive oil. Moderate protein intake using plant-based sources like beans, tofu, and quinoa. Stay well-hydrated and opt for whole foods that support anti-inflammatory balance and cardiovascular health.

Foods to limit

Limit high-sodium, phosphorus, and ultra-processed foods that burden the kidneys. Avoid excessive animal protein and high-potassium choices in advanced dysfunction. Focus on moderation, clean ingredients, and steady hydration to reduce renal strain.

Educational information only — not a diagnosis. Every Pheno result is interpreted in context and reviewed by a physician.

See all 119 markers we test →