Estimated Glomerular Filtration Rate (eGFR) is a sensitive measure of kidney function, especially useful when muscle mass may distort creatinine-based estimates.
Estimated Glomerular Filtration Rate (eGFR) is a sensitive measure of kidney function, especially useful when muscle mass may distort creatinine-based estimates. It reflects how well the kidneys filter Cystatin C — a protein produced by all cells — from the blood. It helps detect early kidney dysfunction, even in individuals with normal creatinine. Low eGFR may signal chronic kidney issues, while elevated levels can sometimes reflect early hyperfiltration or overactivity.
Low eGFR (Cystatin C) can result from chronic kidney disease, systemic inflammation, or cardiovascular issues. Unlike creatinine-based eGFR, this test is less influenced by muscle mass, diet, or age. High Cystatin C may also reflect underlying inflammatory or metabolic disorders, even before overt kidney symptoms appear. Identifying root causes early is key for intervention.
Low eGFR (Cystatin C) may present with fatigue, fluid retention, high blood pressure, or subtle cognitive fog. It can be an early sign of systemic issues. Testing regularly helps track kidney health and adjust lifestyle factors before complications arise.
Include antioxidant-rich, anti-inflammatory foods like berries, olive oil, garlic, and leafy greens to support kidney and vascular health. Hydration from water-rich foods like melon and cucumber can help regulate filtration. Prioritize moderate, plant-based protein intake to avoid overloading the kidneys while still supporting tissue repair.
Limit sodium, processed foods, and sugary beverages, which can worsen inflammation and kidney stress. Avoid excess protein — particularly red meat — and reduce phosphorus-rich items like cola, dairy, and packaged snacks if eGFR is low. Minimizing these stressors preserves filtration capacity.
Educational information only — not a diagnosis. Every Pheno result is interpreted in context and reviewed by a physician.
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