SHBG
SHBG (sex hormone-binding globulin) is a protein that binds sex hormones such as testosterone and oestradiol in the blood.
SHBG (sex hormone-binding globulin) is a protein that binds sex hormones such as testosterone and oestradiol in the blood. It is made mainly in the liver. Hormone bound to SHBG is held in reserve, so the SHBG level affects how much testosterone and oestrogen is free for the body to use. Retesting shows how it changes over time.
SHBG tends to rise with age, with a lot of alcohol, with very low calorie intake and with the contraceptive pill or other oestrogen. It tends to be lower with extra weight around the waist, a diet high in sugar, and high insulin levels. Thyroid hormone levels also play a part.
Foods that help
Vegetables, legumes, whole grains and fibre-rich foods, with enough protein, as part of a varied diet. Regular exercise and good sleep.
Foods to limit
Sugar, sweet drinks and highly processed food. Large amounts of alcohol.
Track it through the year
One value is a snapshot. Following it up shows whether what you changed is working.
Related markers
Educational information only — not a diagnosis. Every result is checked against safe limits, and anything critical is escalated for follow-up.
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