Hormones

DHEA-S

DHEA-S is a precursor to male and female sex hormones, supporting energy, muscle growth, and stress resilience.

What it is

DHEA-S is a precursor to male and female sex hormones, supporting energy, muscle growth, and stress resilience. High DHEA-S may indicate PCOS, adrenal hyperactivity, or hormone imbalances, leading to excess androgen effects. Low DHEA-S is associated with adrenal fatigue, aging, and chronic stress. Monitoring DHEA-S helps assess adrenal function, hormone balance, and aging-related changes, supporting overall metabolic and reproductive health.

What affects your levels

High DHEA-S is often linked to PCOS, adrenal hyperplasia, chronic stress, or excessive exercise. Low DHEA-S can result from adrenal insufficiency, chronic fatigue, aging, or nutrient deficiencies. Poor sleep, prolonged stress, and metabolic disorders also contribute to imbalances. Addressing adrenal function through lifestyle modifications and stress management helps maintain optimal DHEA-S levels, supporting hormone balance and long-term health.

Signs and symptoms

High DHEA-S may cause acne, oily skin, excess hair growth (in women), or menstrual irregularities. Low DHEA-S can lead to fatigue, low libido, muscle loss, and poor stress tolerance. Long-term imbalances impact metabolism, mood, and reproductive function. Regular monitoring, stress reduction, and a nutrient-rich diet help regulate DHEA-S, ensuring optimal adrenal function and hormonal balance.

Foods that help

For low DHEA-S, zinc-rich foods like oysters, pumpkin seeds, and lean meats support adrenal function. Vitamin C-rich foods such as oranges and bell peppers help regulate stress hormones. Healthy fats from avocados, nuts, and olive oil promote hormone production. Adaptogenic herbs like ashwagandha and maca may support adrenal health. A nutrient-dense diet focused on whole foods helps optimize DHEA-S levels and maintain hormonal stability.

Foods to limit

Excess caffeine, processed foods, refined sugars, and alcohol can impair adrenal function, lowering DHEA-S levels. Overtraining and chronic stress also contribute to imbalances. Reducing inflammatory foods and improving stress management supports adrenal resilience, preventing hormone depletion and maintaining balanced DHEA-S levels for optimal metabolic and reproductive health.

Educational information only — not a diagnosis. Every Pheno result is interpreted in context and reviewed by a physician.

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