Liver

AST

Aspartate Aminotransferase (ASAT / AST) is an enzyme found in the liver, heart, and muscles that helps break down amino acids.

What it is

Aspartate Aminotransferase (ASAT / AST) is an enzyme found in the liver, heart, and muscles that helps break down amino acids. High AST levels may indicate liver damage, muscle injury, or heart disease. Low AST levels are usually not concerning but can reflect poor nutrition or vitamin B6 deficiency. Monitoring AST levels helps assess liver and muscle function, guiding interventions to prevent damage and support cardiovascular and metabolic health.

What affects your levels

High AST is often linked to liver disease, excessive alcohol use, viral infections, or muscle damage from intense exercise. Certain medications, high sugar intake, and metabolic disorders may also elevate AST. Low AST is rare but may occur due to malnutrition, aging, or vitamin B6 deficiency. Identifying lifestyle and medical factors that influence AST levels helps maintain organ function and prevent liver-related complications.

Signs and symptoms

High AST levels often present no immediate symptoms but may be linked to liver inflammation, muscle soreness, or digestive issues. Chronic elevation may contribute to fatigue, nausea, jaundice, or an increased risk of metabolic disorders. Low AST is generally not problematic but may indicate nutritional deficiencies. Regular testing, a liver-friendly diet, and reduced alcohol intake help maintain healthy AST levels, ensuring proper metabolic and cardiovascular function.

Foods that help

For liver support, cruciferous vegetables, leafy greens, and citrus fruits provide antioxidants that help lower AST. Lean proteins like chicken, fish, and eggs aid tissue repair. Vitamin B6-rich foods such as bananas, sunflower seeds, and avocados improve enzyme function. Whole grains, legumes, and omega-3-rich foods promote liver detoxification. A well-balanced diet supports AST regulation, reducing the risk of liver dysfunction and muscle breakdown.

Foods to limit

Excess alcohol, fried foods, processed meats, and high-sugar diets can elevate AST and contribute to liver damage. Artificial additives, refined grains, and excessive saturated fats worsen inflammation. Overuse of medications like pain relievers can also strain liver function. Reducing these dietary triggers while focusing on nutrient-dense, anti-inflammatory foods supports liver enzyme balance and metabolic efficiency, preventing further organ stress.

Educational information only — not a diagnosis. Every Pheno result is interpreted in context and reviewed by a physician.

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