Serum Na/K reflects the balance of sodium retention versus potassium excretion, primarily regulated by aldosterone.
Serum Na/K reflects the balance of sodium retention versus potassium excretion, primarily regulated by aldosterone. Elevated ratios suggest aldosterone excess (hypertension risk); low ratios may indicate Addison's disease or ACE inhibitor use.
High: high sodium diet, primary or secondary hyperaldosteronism, thiazide/loop diuretics, Cushing's syndrome, potassium-losing conditions. Low: Addison's disease, ACE inhibitors, potassium-sparing diuretics.
Hypertension, muscle weakness, constipation, fatigue. Severe hypokalaemia: palpitations, arrhythmias.
Potassium-rich foods (bananas, avocado, leafy greens, sweet potato, legumes). Mediterranean or DASH diet lowers sodium and raises potassium.
Processed and ultra-processed foods are the dominant source of dietary sodium (70–80% of daily intake).
Educational information only — not a diagnosis. Every Pheno result is interpreted in context and reviewed by a physician.
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