CRP/Albumin ratio combines an acute-phase reactant (CRP, rises with inflammation) with a negative acute-phase protein (albumin, falls with inflammation and catabolism).
CRP/Albumin ratio combines an acute-phase reactant (CRP, rises with inflammation) with a negative acute-phase protein (albumin, falls with inflammation and catabolism). It distinguishes isolated CRP elevation (low risk) from CRP + falling albumin (systemic catabolic stress).
Chronic inflammation with nutritional or catabolic compromise: ageing, liver disease, severe chronic illness, malignancy, prolonged infection.
Mild elevations are asymptomatic. Severe elevations accompany unintentional weight loss, fatigue, and poor wound healing.
Adequate protein intake (1.0–1.2 g/kg body weight) supports albumin synthesis. Anti-inflammatory diet reduces CRP.
Ultra-processed foods, alcohol excess, and chronic low-protein diets push the ratio in the wrong direction.
Educational information only — not a diagnosis. Every Pheno result is interpreted in context and reviewed by a physician.
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